Planning for epilepsy surgery requires precise localization of the seizure onset zone. This permits physicians to make accurate estimates about the postoperative chances of seizure freedom and the attendant risk. Patients with complex epilepsies may require intracranial electroencephalography (iEEG) to best lateralize and localize the seizure onset zone. Magnetic resonance imaging (MRI) data of implanted intracranial electrodes in a brain is used to confirm correct placement of the intracranial electrodes and to accurately map seizure onset and spread through the brain. However, the relative lack of tools co-registering iEEG with MRI data renders this a time-consuming investigation since for epilepsy specialists who have to manually map this information in 2-dimensional space. Our immersive analytics tool, EPES (Epilepsy Pre- Evaluation Space), provides an application to analyze iEEG data and its fusion with the corresponding intracranial electrodes’ recordings of the brain activity. EPES highlights where a seizure is occurring and how it propagates through the virtual brain generated from the patient MRI data.

EPES provides the following features:

  • Show the MRI scan and the EEG data in a spatial environment
  • Allow doctors to select the start and end of a seizure in any EEG channel
  • Link EEG channels with the specific electrode that generates them
  • Fuse the EEG data with the MRI data by highlighting where a seizure is occurring in the brain
  • Visualizing how seizures propagate through the brain over time Figure 1 conceptualizes this system.